Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 8/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20309118 | 0.76 | ALDH1A1 (0.53) | POLBTP53METALDH1A1LMNA | |
| SCHEMBL29473917 | 0.76 | ALDH1A1 (0.53) | POLBTP53METALDH1A1LMNA | |
| SCHEMBL114725 | 0.76 | ALDH1A1 (0.53) | POLBTP53METALDH1A1LMNA | |
| Methane SCHEMBL28862287 | 0.75 | ALDH1A1 (0.51) | POLBTP53METALDH1A1LMNA | |
| SCHEMBL1163336 | 0.75 | CYP1B1 (0.69) | POLBPSMD14TP53MMP2MET | |
| SCHEMBL5778369 | 0.74 | ALDH1A1 (0.47) | POLBTP53METALDH1A1LMNA | |
| SCHEMBL12182699 | 0.73 | ALDH1A1 (0.44) | POLBALDH1A1SMN1; SMN2MEN1PKM | |
| SCHEMBL14928667 | 0.73 | HTT (0.46) | TP53ALDH1A1SMN1; SMN2PKMKMT2A | |
| Bicarbonate SCHEMBL28288596 | 0.73 | ALDH1A1 (0.59) | POLBMETALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1954298 | 0.73 | MET (0.49) | POLBTP53METALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022000443-A1 | METHODS AND COMPOSITIONS FOR TARGETING TREGS USING CCR8 INHIBITORS | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2022-01-06 | — | — | WO | disclosed |