Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25617121 | 0.83 | SMN1; SMN2 (0.36) | SIGMAR1EPHX1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24458985 | 0.78 | SIGMAR1 (0.37) | SIGMAR1CA12CA1CA2MMP2 | |
| SCHEMBL21362938 | 0.77 | SMN1; SMN2 (0.36) | EPHX1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13997881 | 0.77 | SMN1; SMN2 (0.39) | EPHX1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13997926 | 0.77 | SMN1; SMN2 (0.39) | EPHX1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL10170223 | 0.74 | SIGMAR1 (0.35) | SIGMAR1CA12CA1CA2MMP2 | |
| SCHEMBL9359725 | 0.72 | SMN1; SMN2 (0.33) | EPHX1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL2994447 | 0.71 | MEN1 (0.40) | EPHX1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20625818 | 0.71 | MMP8 (0.37) | SIGMAR1CA12CA1CA2MMP2 | |
| SCHEMBL18827271 | 0.71 | SIGMAR1 (0.33) | SIGMAR1CA12CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022000443-A1 | METHODS AND COMPOSITIONS FOR TARGETING TREGS USING CCR8 INHIBITORS | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2022-01-06 | — | — | WO | disclosed |