Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24171102 | 1.00 | ITGB3 (0.39) | ITGB3ITGA2BALDH1A1JAK2JAK1 | |
| SCHEMBL24171116 | 1.00 | ITGB3 (0.39) | ITGB3ITGA2BALDH1A1JAK2JAK1 | |
| SCHEMBL24171996 | 0.88 | DPP4 (0.40) | ITGB3ITGA2BALDH1A1JAK2JAK1 | |
| SCHEMBL21430433 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BALDH1A1JAK2JAK1 | |
| SCHEMBL24170768 | 0.84 | ITGB3 (0.38) | ITGB3ITGA2BALDH1A1JAK1KDM4E | |
| SCHEMBL23710028 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1JAK2JAK1 | |
| SCHEMBL24171131 | 0.81 | METAP1 (0.39) | ITGB3ITGA2BALDH1A1KDM4EDPP4 | |
| SCHEMBL24171559 | 0.81 | METAP1 (0.39) | ITGB3ITGA2BALDH1A1KDM4EDPP4 | |
| SCHEMBL24170784 | 0.81 | METAP1 (0.39) | ITGB3ITGA2BALDH1A1KDM4EDPP4 | |
| SCHEMBL24170795 | 0.81 | GAA (0.43) | ITGB3ITGA2BALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002290-A1 | TRIFLUOROMETHYL-SUBSTITUTED SULFONAMIDE AS BCL-2-SELECTIVE INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002290-A1 | TRIFLUOROMETHYL-SUBSTITUTED SULFONAMIDE AS BCL-2-SELECTIVE INHIBITOR | BCL2L11, BCL2, BCL2L2 | ITGB3 4779/4885ITGA2B 4539/4885ALDH1A1 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.