Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 17/20 | 0.70 |
| ▸ | ATP4B | P51164 | 17/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417134 | 1.00 | ATP4A (0.70) | ATP4AATP4BNPC1MAPTRAB9A | |
| Iodide SCHEMBL2379575 | 0.99 | ATP4A (0.68) | ATP4AATP4BNPC1MAPTRAB9A | |
| Iodide SCHEMBL2379579 | 0.99 | ATP4A (0.68) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL823907 | 0.83 | ATP4A (1.00) | ATP4AATP4BNPC1MAPTRAB9A | |
| Bromide SCHEMBL825847 | 0.81 | ATP4A (0.97) | ATP4AATP4BNPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL827560 | 0.79 | ATP4A (0.91) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL8651695 | 0.76 | ATP4A (0.53) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL2418997 | 0.73 | ATP4A (0.61) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL2378390 | 0.73 | ADORA3 (0.50) | ATP4AATP4BNPC1RAB9A | |
| SCHEMBL2378386 | 0.73 | ADORA3 (0.50) | ATP4AATP4BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716127-B1 | GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBVIE DEUTSCHLAND (DE) | 2014-08-06 | — | — | EP | disclosed |
| EP-2380885-A1 | Guanidine compounds and use of same as binding partners for 5-HT5 receptors | Abbott GmbH & Co. KG (DE) | 2011-10-26 | — | — | EP | disclosed |
| EP-2366392-A1 | Guanidine compounds and use of same as binding partners for 5-HT5 receptors | Abbott GmbH & Co. KG (DE) | 2011-09-21 | — | — | EP | disclosed |
| EP-2366697-A1 | Guanidine compounds and use of same as binding partners for 5-HT5 receptors | Abbott GmbH & Co. KG (DE) | 2011-09-21 | — | — | EP | disclosed |
| EP-1716127-A2 | GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005082871-A2 | GUANIDINE COMPOUNDS, AND USE THEREOF AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2005-09-09 | — | — | WO | disclosed |