Styrene

Styrene

SCHEMBL2417399

C=C(C=CC(=O)O)C(=O)OCCCCCC(C)C.C=Cc1ccccc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
HTT P42858 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ESR1 P03372 1/20 0.35
RARB P10826 1/20 0.35
HCAR2 Q8TDS4 5/20 0.35
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
PPIA P62937 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL18297752 0.87 HCAR2 (0.49) ALDH1A1SMN1; SMN2KDM4ELMNAMAPT
Styrene SCHEMBL8094495 0.87 HCAR2 (0.49) ALDH1A1SMN1; SMN2KDM4ELMNAMAPT
SCHEMBL3246416 0.87 HCAR2 (0.44) ALDH1A1HTTESR1RARBHCAR2
SCHEMBL7525257 0.86 ALDH1A1 (0.46) ALDH1A1HTTNPSR1KDM4ELMNA
Styrene SCHEMBL4619670 0.86 HTT (0.48) ALDH1A1HTTNPSR1SMN1; SMN2LMNA
Styrene SCHEMBL250640 0.84 HCAR2 (0.47) ALDH1A1SMN1; SMN2KDM4ELMNAMAPT
SCHEMBL9837758 0.83 ALDH1A1 (0.38) ALDH1A1HTTNPSR1SMN1; SMN2KDM4E
Styrene SCHEMBL28609445 0.82 TSHR (0.45) ALDH1A1HTTNPSR1SMN1; SMN2KDM4E
Styrene SCHEMBL8516972 0.82 HCAR2 (0.44) ALDH1A1SMN1; SMN2KDM4ELMNAMAPT
Styrene SCHEMBL8082269 0.81 TSHR (0.47) ALDH1A1SMN1; SMN2LMNAESR1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105399971-B Composite layer 3M创新有限公司 2019-03-01 CN disclosed
EP-1255575-B2 FOAM/FILM COMPOSITE MEDICAL ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2018-12-12 EP disclosed
EP-2550146-B1 EXTRUSION DIE AND METHOD FOR MAKING MULTIPLE STRIPE EXTRUDATE 3M INNOVATIVE PROPERTIES CO (US) 2018-09-26 EP disclosed
US-20170197347-A1 COMPOSITE LAYER 3M INNOVATIVE PROPERTIES CO (US) 2017-07-13 US disclosed
US-9327429-B2 Extrusion die element, extrusion die and method for making multiple stripe extrudate 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-05-03 US disclosed
EP-2550156-A2 COMPOSITE LAYER 3M Innovative Properties Company (US) 2013-01-30 EP disclosed
EP-2550146-A1 EXTRUSION DIE ELEMENT, EXTRUSION DIE AND METHOD FOR MAKING MULTIPLE STRIPE EXTRUDATE 3M Innovative Properties Company (US) 2013-01-30 EP disclosed
US-20130009336-A1 EXTRUSION DIE ELEMENT, EXTRUSION DIE AND METHOD FOR MAKING MULTIPLE STRIPE EXTRUDATE 3M INNOVATIVE PROPERTIES COMPANY 2013-01-10 US disclosed
US-20130004729-A1 COMPOSITE LAYER 3M INNOVATIVE PROPERTIES COMPANY 2013-01-03 US disclosed
WO-2011119325-A2 COMPOSITE LAYER 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-09-29 WO disclosed
EP-1035821-A1 NASAL DILATOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-09-20 EP disclosed
EP-1035813-A1 NONWOVEN COHESIVE WRAP MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-09-20 EP disclosed
EP-1036122-A1 REPOSITIONABLE SHEETS WITH A NONWOVEN WEB OF PRESSURE-SENSITIVE ADHESIVE FIBERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-09-20 EP disclosed
US-6107222-A Repositionable sheets with a nonwoven web of pressure-sensitive adhesive fibers 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-08-22 US disclosed
US-6083856-A Acrylate copolymeric fibers 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-07-04 US disclosed
WO-2000032142-A1 WET SKIN ADHESIVE ARTICLE 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-06-08 WO disclosed
WO-1999027880-A1 NASAL DILATOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-10 WO disclosed
WO-1999028539-A1 ACRYLATE COPOLYMERIC FIBERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-10 WO disclosed
WO-1999028402-A1 REPOSITIONABLE SHEETS WITH A NONWOVEN WEB OF PRESSURE-SENSITIVE ADHESIVE FIBERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-10 WO disclosed
WO-1999027875-A1 NONWOVEN COHESIVE WRAP MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-10 WO disclosed