SCHEMBL24174792

SCHEMBL24174792

CCSc1c(-c2nc3cc4c(cc3n2C)OC(F)(F)C(F)(F)O4)nc(-c2ccc(Cl)cc2)n1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 3/20 0.34
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
PRSS12 P56730 2/20 0.33
GABRA2 P47869 3/20 0.32
GABRB2 P47870 3/20 0.32
POLB P06746 1/20 0.32
KDM4E B2RXH2 3/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
PTGS2 P35354 3/20 0.31
PTGES O14684 1/20 0.31
CYP1A2 P05177 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24175632 0.87
SCHEMBL24175437 0.84
SCHEMBL24174793 0.83 PTGS2 (0.37) PTGDR2PRSS12GABRA2GABRB2PTGS2
SCHEMBL24175239 0.83
SCHEMBL24174545 0.82 PRSS12 (0.32) PTGDR2MEN1MAPTRAB9AKMT2A
SCHEMBL24174578 0.82
SCHEMBL30404301 0.80 PTGS2 (0.37) PTGDR2MEN1KMT2APRSS12PTGS2
SCHEMBL25350128 0.80 PTGS2 (0.37) PTGDR2MEN1KMT2APRSS12PTGS2
SCHEMBL24175258 0.80
SCHEMBL24174510 0.78 PDE10A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230247994-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-08-10 US disclosed
US-20230247994-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-08-10 US disclosed
US-20230247994-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2023-08-10 US disclosed
EP-4175961-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS Bayer Aktiengesellschaft (DE) 2023-05-10 EP disclosed
WO-2022002818-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2022-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230247994-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS CHRM1, DDT, H1-0 PTGDR2 3278/4885MEN1 327/4885MAPT 4309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.