Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19709119 | 1.00 | MGLL (0.37) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL20801815 | 0.89 | MGLL (0.49) | MGLLHPGDCYP2C19ALDH1A1 | |
| SCHEMBL26875609 | 0.88 | MGLL (0.46) | MGLLHPGDCYP2C19ALDH1A1 | |
| SCHEMBL24240484 | 0.87 | MGLL (0.40) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL26707214 | 0.87 | MGLL (0.42) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL21780805 | 0.87 | MGLL (0.42) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL23221936 | 0.85 | PTGS1 (0.37) | MGLLSMN1; SMN2HPGDHTTCYP2C19 | |
| SCHEMBL20287749 | 0.85 | MGLL (0.33) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL18086985 | 0.84 | MGLL (0.38) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL20258360 | 0.84 | MGLL (0.38) | MGLLPOLBHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022001864-A1 | ANTIBODY-DRUG CONJUGATE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 昆山新蕴达生物科技有限公司 | 2022-01-06 | — | — | WO | disclosed |