Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26707214 | 0.91 | MGLL (0.42) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL21780805 | 0.91 | MGLL (0.42) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL13407964 | 0.88 | MGLL (0.37) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL20802043 | 0.88 | MGLL (0.54) | MGLLSMN1; SMN2HPGDHTTCYP2C19 | |
| SCHEMBL31520126 | 0.88 | MGLL (0.54) | MGLLSMN1; SMN2HPGDHTTCYP2C19 | |
| SCHEMBL18086985 | 0.88 | MGLL (0.38) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL20258360 | 0.88 | MGLL (0.38) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL25834988 | 0.87 | POLB (0.44) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL17841886 | 0.87 | MGLL (0.37) | MGLLPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL24176122 | 0.87 | MGLL (0.37) | MGLLPOLBHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3949969-A2 | BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF | Silverback Therapeutics, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |