Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAGH | Q16775 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21951992 | 0.88 | HAGH (1.00) | HAGHALDH1A1HPGDGAAKDM4E | |
| SCHEMBL21964046 | 0.85 | HAGH (0.84) | HAGHALDH1A1HPGDGAAKDM4E | |
| SCHEMBL21963930 | 0.83 | HAGH (0.75) | HAGHALDH1A1HPGDGAAKDM4E | |
| SCHEMBL24176460 | 0.82 | HAGH (0.67) | HAGHALDH1A1HPGDGAAKDM4E | |
| SCHEMBL21963935 | 0.78 | HAGH (0.81) | HAGHALDH1A1HPGDGAAKDM4E | |
| SCHEMBL21964146 | 0.76 | HAGH (0.69) | HAGHALDH1A1HPGDGAAKDM4E | |
| SCHEMBL21964112 | 0.76 | HAGH (0.72) | HAGHALDH1A1HPGDGAAKDM4E | |
| SCHEMBL21964058 | 0.75 | HAGH (0.67) | HAGHALDH1A1HPGDGAAKDM4E | |
| SCHEMBL24176313 | 0.74 | HAGH (0.73) | HAGHALDH1A1HPGDGAAKDM4E | |
| SCHEMBL21963934 | 0.74 | HAGH (0.65) | HAGHALDH1A1HPGDGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220000841-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | UNIVERSITÉ DE MONTPELLIER (FR) | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000841-A1 | INHIBITORS OF METALLO-BETA-LACTAMASES | MGAM, LCT, MGAM2 | HAGH 1320/4885ALDH1A1 547/4885HPGD 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.