Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL30277481 | 0.99 | MAPT (0.49) | MAPTKDM4EL3MBTL1NPSR1TDP1 | |
| SCHEMBL24177106 | 0.78 | MAPT (0.46) | MAPTKDM4EL3MBTL1NPSR1SMN1; SMN2 | |
| Bromide SCHEMBL30277449 | 0.77 | MAPT (0.45) | MAPTKDM4EL3MBTL1NPSR1SMN1; SMN2 | |
| SCHEMBL3118498 | 0.70 | MAPT (0.55) | MAPTKDM4EL3MBTL1NPSR1TDP1 | |
| SCHEMBL3126879 | 0.70 | MAPT (0.55) | MAPTKDM4EL3MBTL1NPSR1IDO1 | |
| Hydrochloric Acid SCHEMBL831427 | 0.69 | MAPT (0.54) | MAPTKDM4EL3MBTL1NPSR1IDO1 | |
| Hydrochloric Acid SCHEMBL834232 | 0.69 | MAPT (0.54) | MAPTKDM4EL3MBTL1NPSR1TDP1 | |
| SCHEMBL1872279 | 0.69 | MAPT (0.51) | MAPTKDM4EL3MBTL1NPSR1TDP1 | |
| SCHEMBL24176868 | 0.68 | MAPT (0.71) | MAPTKDM4EL3MBTL1NPSR1SMN1; SMN2 | |
| Bromide SCHEMBL30277607 | 0.68 | MAPT (0.70) | MAPTKDM4EL3MBTL1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | DDC, IL4I1, ING2 | MAPT 3880/4885KDM4E 571/4885L3MBTL1 3259/4885 |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | DDC, IL4I1, ING2 | MAPT 3880/4885KDM4E 571/4885L3MBTL1 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.