Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938207 | 0.91 | ALDH1A1 (0.69) | ALDH1A1KMT2ANR1H4EPHX2SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL11033093 | 0.84 | TSHR (0.60) | ALDH1A1KMT2ASMN1; SMN2SRD5A2HPGD | |
| SCHEMBL28423573 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KMT2ANR1H4EPHX2SMN1; SMN2 | |
| SCHEMBL249385 | 0.83 | KMT2A (0.66) | ALDH1A1KMT2ANR1H4EPHX2SMN1; SMN2 | |
| SCHEMBL3503996 | 0.82 | ALDH1A1 (0.81) | ALDH1A1KMT2ANR1H4EPHX2SMN1; SMN2 | |
| SCHEMBL7723455 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KMT2ANR1H4EPHX2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL944164 | 0.81 | KMT2A (0.63) | ALDH1A1KMT2ANR1H4EPHX2SMN1; SMN2 | |
| SCHEMBL7721622 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2ANR1H4EPHX2SMN1; SMN2 | |
| SCHEMBL18828911 | 0.81 | S1PR1 (0.57) | ALDH1A1KMT2ASMN1; SMN2MEN1S1PR2 | |
| SCHEMBL7721679 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2ANR1H4EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002287-A1 | INDAZOLE KINASE INHIBITOR AND USE THEREOF | Tarapeutics Science Inc. (CN) | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002287-A1 | INDAZOLE KINASE INHIBITOR AND USE THEREOF | FLT3, FGFR1, FLT1 | ALDH1A1 1239/4885KMT2A 1434/4885NR1H4 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.