Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL944164 | 0.98 | KMT2A (0.63) | KMT2AALDH1A1NR1H4EPHX2SRD5A2 | |
| SCHEMBL5616342 | 0.91 | KMT2A (0.56) | KMT2AALDH1A1NR1H4EPHX2SRD5A2 | |
| N-Benzylmethylamine SCHEMBL28452678 | 0.88 | KDM4E (0.65) | KMT2AALDH1A1NR1H4EPHX2SRD5A2 | |
| SCHEMBL5499807 | 0.85 | KMT2A (0.50) | KMT2AALDH1A1NR1H4EPHX2SRD5A2 | |
| SCHEMBL11864213 | 0.83 | ALDH1A1 (0.62) | KMT2AALDH1A1NR1H4EPHX2SRD5A2 | |
| SCHEMBL24178010 | 0.83 | ALDH1A1 (0.59) | KMT2AALDH1A1NR1H4EPHX2SRD5A2 | |
| SCHEMBL10131958 | 0.83 | KMT2A (0.68) | KMT2AALDH1A1NR1H4EPHX2KDM4E | |
| SCHEMBL3503996 | 0.82 | ALDH1A1 (0.81) | KMT2AALDH1A1NR1H4EPHX2TP53 | |
| SCHEMBL8039506 | 0.82 | KDM4E (0.57) | ALDH1A1SRD5A2KDM4EMAPTCYP3A4 | |
| SCHEMBL3882642 | 0.81 | PLA2G10 (0.57) | KMT2AALDH1A1NR1H4EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313703-B1 | PRODRUGS TO NMDA RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2008-02-13 | — | — | EP | claimed |
| US-7169759-B1 | Tetrapeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2007-01-30 | — | — | US | claimed |
| EP-1313703-A1 | PRODRUGS TO NMDA RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-28 | — | — | EP | claimed |
| US-6407235-B1 | A NMDA (N-METHYL-D-ASPARTATE)-RECEPTOR-SUBTYPE SELECTIVE BLOCKERS; PRODRUGS HAVE IMPROVED SOLUBILITY AND ARE HYDROLYZED IN VIVO; FOR EXAMPLE, THE 4-AMINOMETHYL-BENZOIC ACID ESTER OF THE PHENOL, OR THE PHOSPHATE ESTER | HOFFMANN-LA ROCHE INC. | 2002-06-18 | — | — | US | claimed |
| US-20020040037-A1 | Prodrug acid esters of [2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethansulfonyl]phenol | EVOTEC INTERNATIONAL GMBH (DE) | 2002-04-04 | — | — | US | claimed |
| EP-1192177-A1 | STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE | Elan Pharmaceuticals, Inc. (US) | 2002-04-03 | — | — | EP | claimed |
| WO-2002016321-A1 | PRODRUGS TO NMDA RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-28 | — | — | WO | claimed |
| WO-2000077030-A1 | STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE | ELAN PHARMACEUTICALS, INC. (US) | 2000-12-21 | — | — | WO | claimed |
| CN-114539098-B | Difunctional HDAC6 inhibitor, synthesis method and application | 青岛大学 | 2024-05-24 | — | — | CN | disclosed |
| EP-3998260-B1 | SGC STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2023-11-01 | — | — | EP | disclosed |
| CN-111205244-B | Thiazolo-ring compound, preparation method, intermediate and application thereof | 上海科技大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-109369635-B | Compound or pharmaceutically acceptable salt thereof, application thereof and pharmaceutical composition | 赛克里翁治疗有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-11674136-B2 | DNA-templated macrocycle library | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230152306-A1 | NANOPARTICLES FOR SENSING USE AND PRODUCTION METHOD FOR SAME | TearExo Inc. (JP) | 2023-05-18 | — | — | US | disclosed |
| WO-2002016321-A1 | PRODRUGS TO NMDA RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-28 | — | — | WO | disclosed |
| US-6291673-B1 | Folic acid derivatives | PURDUE RESEARCH FOUNDATION | 2001-09-18 | — | — | US | disclosed |
| US-6022956-A | Water-soluble halotriazine-containing axo compounds, preparation thereof and use thereof as dyes | DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2000-02-08 | — | — | US | disclosed |
| EP-0957135-A1 | Water-soluble halotriazine-containing azo compounds, preparation thereof and use thereof as dyes | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 1999-11-17 | — | — | EP | disclosed |
| US-5912251-A | ENZYME INHIBITORS | CHELSEA THERAPEUTICS, INC. | 1999-06-15 | — | — | US | disclosed |
| WO-1999020626-A1 | FOLIC ACID DERIVATIVES | PURDUE RESEARCH FOUNDATION (US) | 1999-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11674136-B2 | DNA-templated macrocycle library | IDE, IAPP, POLRMT | KMT2A 3958/4885ALDH1A1 4658/4885NR1H4 1083/4885 |
| US-20020040037-A1 | Prodrug acid esters of [2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethansulfonyl]phenol | HAO2, CYP2B6, CBR1 | KMT2A 2738/4885ALDH1A1 149/4885NR1H4 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.