Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24178266 | 1.00 | GNPAT (0.52) | GNPATPTPN1LTA4HCTSSCTSK | |
| SCHEMBL24178271 | 0.95 | PTPN1 (0.49) | GNPATPTPN1LTA4HCTSSCTSK | |
| SCHEMBL24178269 | 0.95 | PTPN1 (0.49) | GNPATPTPN1LTA4HCTSSCTSK | |
| SCHEMBL24178183 | 0.92 | CTSB (0.52) | LTA4HANPEPBACE1CTSB | |
| SCHEMBL24178171 | 0.92 | CTSB (0.52) | LTA4HANPEPBACE1CTSB | |
| SCHEMBL24178185 | 0.88 | SMN1; SMN2 (0.46) | LTA4HANPEPBACE1CTSBFNTA | |
| SCHEMBL24178184 | 0.88 | PTPN1 (0.43) | PTPN1LTA4HANPEPMMECTSB | |
| SCHEMBL25466140 | 0.87 | CPA1 (0.50) | GNPATPTPN1CTSBCTSL | |
| SCHEMBL25465177 | 0.87 | CPA1 (0.50) | GNPATPTPN1CTSBCTSL | |
| SCHEMBL8836882 | 0.86 | GNPAT (0.61) | GNPATPTPN1LTA4HANPEPMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912742-B2 | Heterologous production of leupeptin protease inhibitors and analogs thereof | YALE UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| US-20220002354-A1 | HETEROLOGOUS PRODUCTION OF LEUPEPTIN PROTEASE INHIBITORS AND ANALOGS THEREOF | YALE UNIVERSITY | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912742-B2 | Heterologous production of leupeptin protease inhibitors and analogs thereof | LPXN, LAP3, PEPD | GNPAT 513/4885PTPN1 2403/4885LTA4H 1039/4885 |
| US-20220002354-A1 | HETEROLOGOUS PRODUCTION OF LEUPEPTIN PROTEASE INHIBITORS AND ANALOGS THEREOF | LPXN, LAP3, PEPD | GNPAT 513/4885PTPN1 2403/4885LTA4H 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.