Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153952 | 1.00 | HTR2A (0.39) | HTR2AALDH1A1 | |
| SCHEMBL10094588 | 0.78 | — | — | |
| SCHEMBL15755391 | 0.74 | TSHR (0.32) | ALDH1A1 | |
| SCHEMBL15755393 | 0.74 | TSHR (0.32) | ALDH1A1 | |
| SCHEMBL7928919 | 0.69 | — | — | |
| SCHEMBL26996497 | 0.69 | — | — | |
| SCHEMBL21846946 | 0.69 | HTR2A (0.43) | HTR2AALDH1A1 | |
| SCHEMBL4544179 | 0.69 | — | — | |
| SCHEMBL28027671 | 0.68 | — | — | |
| SCHEMBL24178278 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448386-B2 | Processes for the preparation of substituted 1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indoles | HOFFMANN-LA ROCHE INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-11873305-B2 | Processes for synthesis of substituted indole intermediates for the synthesis of serd compounds | GENENTECH, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11873305-B2 | Processes for synthesis of substituted indole intermediates for the synthesis of serd compounds | GENENTECH, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| CN-115916750-A | Process for preparing SERD tricyclic compounds having substituted phenyl or pyridyl moieties | 基因泰克公司 | 2023-04-04 | — | — | CN | disclosed |
| US-20220002304-A1 | PROCESSES FOR MAKING SERD TRICYCLIC COMPOUNDS HAVING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY | GENENTECH, INC. (US) | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873305-B2 | Processes for synthesis of substituted indole intermediates for the synthesis of serd compounds | WEE1, WEE2, INMT | HTR2A 728/4885ALDH1A1 2335/4885 |
| US-20220002304-A1 | PROCESSES FOR MAKING SERD TRICYCLIC COMPOUNDS HAVING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY | PLK2, CHEK1, PLK4 | HTR2A 986/4885ALDH1A1 1315/4885 |
| US-12448386-B2 | Processes for the preparation of substituted 1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indoles | WEE1, WEE2, PGK1 | HTR2A 337/4885ALDH1A1 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.