Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180164 | 0.93 | PARP10 (0.43) | HTR2CHTR2BHTR2APARP10PARP15 | |
| SCHEMBL24720454 | 0.85 | PIM1 (0.39) | HTR2CHTR2BHTR2APARP10PARP15 | |
| SCHEMBL24180160 | 0.77 | HTR2A (0.38) | HTR2CHTR2BHTR2APARP10PARP15 | |
| SCHEMBL28333031 | 0.76 | HTR2A (0.56) | HTR2CHTR2BHTR2ATLR9TLR8 | |
| SCHEMBL23914594 | 0.76 | HTR2C (0.42) | HTR2CHTR2BHTR2APARP10PARP15 | |
| SCHEMBL24180204 | 0.76 | HTR2C (0.42) | HTR2CHTR2BHTR2APARP10PARP15 | |
| SCHEMBL24180096 | 0.75 | HTR2C (0.55) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL20354811 | 0.75 | HTR2C (0.41) | HTR2CHTR2BHTR2APARP10PARP15 | |
| SCHEMBL2546337 | 0.74 | HTR2C (0.47) | HTR2CHTR2BHTR2APARP10PARP15 | |
| SCHEMBL28844733 | 0.74 | HTR2C (0.43) | HTR2CHTR2BHTR2APARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704118-B1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-01-12 | — | — | EP | disclosed |