Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180220 | 0.93 | HTR2C (0.44) | PARP10PARP15HTR2AHTR2CHTR2B | |
| SCHEMBL29786587 | 0.81 | HTR2A (0.41) | PARP10CDK2MCHR1PARP15HTR2A | |
| SCHEMBL20472323 | 0.81 | HTR2A (0.41) | PARP10CDK2MCHR1PARP15HTR2A | |
| SCHEMBL24720454 | 0.79 | PIM1 (0.39) | PARP10PARP15HTR2AHTR2CHTR2B | |
| SCHEMBL24499219 | 0.76 | SCN9A (0.39) | PARP10SCN9ASCN5A | |
| SCHEMBL28331550 | 0.76 | SCN9A (0.42) | PARP10HTR2AHTR2CHTR2BSCN9A | |
| SCHEMBL22069559 | 0.75 | PARP10 (0.45) | PARP10CDK2MCHR1PARP15HTR2A | |
| SCHEMBL30286653 | 0.75 | PARP10 (0.45) | PARP10CDK2MCHR1HTR2AHTR2C | |
| SCHEMBL24180070 | 0.75 | PARP10 (0.43) | PARP10MCHR1PARP15 | |
| SCHEMBL12261484 | 0.75 | MCHR1 (0.49) | PARP10CDK2MCHR1PARP15HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704118-B1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-01-12 | — | — | EP | disclosed |