Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | OXTR | P30559 | 4/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20147415 | 0.85 | SLC6A4 (0.53) | SLC6A4PDE9A | |
| SCHEMBL25807458 | 0.81 | SLC6A4 (0.47) | SLC6A4OXTRAVPR1A | |
| SCHEMBL4129984 | 0.81 | SLC6A4 (0.46) | SLC6A4OXTRAVPR1ATACR1AVPR2 | |
| SCHEMBL12374723 | 0.77 | SLC6A4 (0.56) | SLC6A4 | |
| SCHEMBL9450771 | 0.75 | OXTR (0.54) | OXTRAVPR1ARBP4 | |
| SCHEMBL20070185 | 0.75 | HSD11B1 (0.48) | SLC6A4 | |
| SCHEMBL2282399 | 0.75 | SLC6A4 (0.78) | SLC6A4 | |
| SCHEMBL10057698 | 0.74 | HRH3 (0.45) | SLC6A4PDE9A | |
| SCHEMBL27478491 | 0.74 | CSNK2A1 (0.59) | — | |
| SCHEMBL9450773 | 0.74 | OXTR (0.53) | OXTRAVPR1ARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022010537-A1 | GAS41 INHIBITORS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-01-13 | — | — | WO | disclosed |