Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810869 | 0.88 | HPGD (0.54) | HPGDALDH1A1POLBYEATS4HRH3 | |
| SCHEMBL14328433 | 0.85 | ALDH1A1 (0.54) | HPGDALDH1A1POLBYEATS4HRH3 | |
| SCHEMBL27810871 | 0.85 | HPGD (0.55) | HPGDALDH1A1POLBYEATS4HRH3 | |
| SCHEMBL3254670 | 0.78 | HPGD (0.62) | HPGDALDH1A1POLBYEATS4HRH3 | |
| SCHEMBL13155877 | 0.78 | HPGD (0.62) | HPGDALDH1A1POLBYEATS4HRH3 | |
| SCHEMBL30340462 | 0.76 | HPGD (0.64) | HPGDALDH1A1POLBYEATS4HRH3 | |
| SCHEMBL4157157 | 0.76 | HPGD (0.66) | HPGDALDH1A1POLBYEATS4HRH3 | |
| SCHEMBL24188555 | 0.76 | HPGD (0.46) | HPGDALDH1A1POLBYEATS4HRH3 | |
| SCHEMBL12272028 | 0.75 | DAO (0.60) | HPGDALDH1A1POLBGAAMAPT | |
| SCHEMBL2409095 | 0.75 | DAO (0.60) | HPGDALDH1A1POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858925-B2 | GAS41 inhibitors and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-01-02 | — | — | US | disclosed |
| US-11858925-B2 | GAS41 inhibitors and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220017509-A1 | GAS41 INHIBITORS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-20 | — | — | US | disclosed |
| WO-2022010537-A1 | GAS41 INHIBITORS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858925-B2 | GAS41 inhibitors and methods of use thereof | GAS6, HIF1AN, TMEM41B | HPGD 3148/4885ALDH1A1 4237/4885POLB 3975/4885 |
| US-20220017509-A1 | GAS41 INHIBITORS AND METHODS OF USE THEREOF | GAS6, HIF1AN, TMEM41B | HPGD 3148/4885ALDH1A1 4237/4885POLB 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.