Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25639624 | 0.94 | SIGMAR1 (0.52) | SIGMAR1DNM1EPHX1ALDH1A1MEN1 | |
| SCHEMBL11254008 | 0.89 | CYP1A2 (0.52) | SIGMAR1EPHX1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL27603789 | 0.89 | CYP1A2 (0.52) | SIGMAR1EPHX1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL22260597 | 0.89 | SIGMAR1 (0.67) | SIGMAR1DNM1EPHX1TSHR | |
| SCHEMBL29904852 | 0.87 | EPHX1 (0.48) | SIGMAR1EPHX1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL28358906 | 0.87 | EPHX1 (0.48) | SIGMAR1EPHX1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL29904850 | 0.87 | EPHX1 (0.48) | SIGMAR1EPHX1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL23742068 | 0.87 | SIGMAR1 (0.62) | SIGMAR1DNM1MEN1KMT2ATSHR | |
| SCHEMBL4004983 | 0.87 | EPHX1 (0.48) | SIGMAR1EPHX1ALDH1A1TSHRCYP1A2 | |
| SCHEMBL29455101 | 0.87 | EPHX1 (0.48) | SIGMAR1EPHX1ALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220008635-A1 | METHODS AND APPARATUSES USING UREA PERMSELECTIVE DIFFUSION THROUGH CHARGED MEMBRANES | VANTIVE HEALTH GMBH (CH) | 2022-01-13 | — | — | US | disclosed |