Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17531163 | 0.82 | ALDH1A1 (0.50) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL29955318 | 0.80 | GAA (0.47) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2369964 | 0.79 | CNR2 (0.50) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL31195879 | 0.79 | GAA (0.45) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL16908180 | 0.79 | SMPD3 (0.50) | ALDH1A1GAAHPGDKDM4ECNR2 | |
| SCHEMBL25333250 | 0.79 | GAA (0.45) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL26248560 | 0.79 | GAA (0.42) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL18394769 | 0.74 | PKM (0.57) | ALDH1A1GAAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL12701772 | 0.73 | ALDH1A1 (0.56) | ALDH1A1GAAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL24195931 | 0.72 | SMPD3 (0.47) | ALDH1A1GAAHPGDKDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008911-A1 | BENZODIAZEPINE DERIVATIVES USEFUL IN TREATING A RESPIRATORY SYNCYTIAL VIRUS INFECTION | ReViral Limited (GB) | 2022-01-13 | — | — | WO | disclosed |