SCHEMBL24196259

SCHEMBL24196259

C=C(C)C(=O)OCCOC(=O)c1ccc(C(=O)Oc2ccc(OC(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.58
KMT2A Q03164 9/20 0.55
MAPT P10636 8/20 0.55
LMNA P02545 2/20 0.55
KDM4E B2RXH2 2/20 0.55
HSP90AA1 P07900 2/20 0.55
TDP1 Q9NUW8 3/20 0.52
POLB P06746 1/20 0.52
APEX1 P27695 1/20 0.52
HTT P42858 1/20 0.52
PARP10 Q53GL7 1/20 0.51
MEN1 O00255 5/20 0.50
ALDH1A1 P00352 4/20 0.50
HPGD P15428 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
PKM P14618 1/20 0.49
THRB P10828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21422396 0.94 POLB (0.54) ELANEKMT2AMAPTLMNAKDM4E
SCHEMBL24196279 0.92 TDP1 (0.60) ELANEKMT2AMAPTLMNAKDM4E
SCHEMBL436276 0.90 LMNA (0.61) ELANEKMT2AMAPTLMNATDP1
SCHEMBL18960041 0.89 TDP1 (0.60) ELANEKMT2AMAPTLMNAKDM4E
SCHEMBL24196277 0.88 ELANE (0.51) ELANEKMT2AMAPTLMNAKDM4E
SCHEMBL18931421 0.88 MAPT (0.56) ELANEKMT2AMAPTLMNAKDM4E
SCHEMBL18931422 0.88 MAPT (0.56) ELANEKMT2AMAPTLMNAKDM4E
SCHEMBL18418414 0.88 ELANE (0.50) ELANEKMT2AMAPTLMNAKDM4E
SCHEMBL17481306 0.88 ELANE (0.50) ELANEKMT2AMAPTLMNAKDM4E
SCHEMBL19985664 0.86 TDP1 (0.47) ELANEKMT2AMAPTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11732191-B2 Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-11732191-B2 Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-20220010209-A1 COMPOUND, POLYMERIZABLE COMPOSITION, CURED PRODUCT, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-01-13 US disclosed