SCHEMBL24196276

SCHEMBL24196276

C=CC(=O)OCCOC(=O)c1ccc(C(=O)Oc2ccc(OC(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.57
PARP10 Q53GL7 1/20 0.53
TDP1 Q9NUW8 3/20 0.50
KMT2A Q03164 10/20 0.48
MAPT P10636 9/20 0.48
MEN1 O00255 5/20 0.48
RAB9A P51151 2/20 0.48
LMNA P02545 2/20 0.47
KDM4E B2RXH2 2/20 0.47
HSP90AA1 P07900 2/20 0.47
ALDH1A1 P00352 5/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PKM P14618 1/20 0.47
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
HPGD P15428 3/20 0.45
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24196267 0.92 TDP1 (0.55) THRBPARP10TDP1KMT2AMAPT
SCHEMBL434163 0.89 THRB (0.65) THRBTDP1KMT2ARAB9ALMNA
SCHEMBL24196595 0.88 TDP1 (0.51) THRBPARP10TDP1KMT2AMAPT
SCHEMBL16885031 0.88 THRB (0.61) THRBPARP10TDP1KMT2AMAPT
SCHEMBL24196281 0.88 THRB (0.57) THRBPARP10KMT2AMAPTMEN1
SCHEMBL16133505 0.87 MAPT (0.53) THRBKMT2AMAPTRAB9ALMNA
SCHEMBL5517403 0.86 THRB (0.62) THRBPARP10TDP1KMT2AMAPT
SCHEMBL5530467 0.86 THRB (0.62) THRBPARP10TDP1KMT2AMAPT
SCHEMBL14365182 0.86 THRB (0.55) THRBTDP1KMT2AMAPTMEN1
SCHEMBL19978527 0.86 THRB (0.55) THRBTDP1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11732191-B2 Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-11732191-B2 Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-20220010209-A1 COMPOUND, POLYMERIZABLE COMPOSITION, CURED PRODUCT, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-01-13 US disclosed