Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21262379 | 0.98 | AR (0.44) | ARCNR2UBE2THRH4IP6K1 | |
| SCHEMBL24196358 | 0.86 | ELOVL1 (0.44) | CNR2KCNQ3KCNQ2ALDH1A1CRHBP | |
| SCHEMBL24195983 | 0.84 | HRH4 (0.47) | HRH4ALDH1A1 | |
| SCHEMBL14910307 | 0.84 | KDM4E (0.47) | CNR2KCNQ3KCNQ2ALDH1A1CRHBP | |
| SCHEMBL12488177 | 0.82 | CNR2 (0.44) | ARCNR2UBE2THRH4IP6K1 | |
| SCHEMBL30280743 | 0.82 | CNR2 (0.44) | ARCNR2UBE2THRH4IP6K1 | |
| SCHEMBL20089110 | 0.81 | CNR2 (0.46) | ARCNR2UBE2THRH4IP6K1 | |
| SCHEMBL24195788 | 0.80 | GRIN2D (0.35) | CNR2HRH4ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL15544107 | 0.79 | CNR2 (0.41) | ARCNR2UBE2THRH4IP6K1 | |
| SCHEMBL24196360 | 0.78 | SMO (0.47) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |