SCHEMBL24197

SCHEMBL24197

O=Cc1cccc(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1574019 1.00 NFE2L2 (0.65)
SCHEMBL18472616 1.00
SCHEMBL29359478 1.00
Hydrochloric Acid SCHEMBL29768617 0.98 NFE2L2 (0.62)
Ammonia Solution, Strong SCHEMBL27509053 0.98 NFE2L2 (0.62)
Hydrochloric Acid SCHEMBL29084496 0.98 NFE2L2 (0.62)
Cyclohexane SCHEMBL268585 0.93 NFE2L2 (0.58)
SCHEMBL17686281 0.91 NFE2L2 (0.64)
SCHEMBL3819301 0.87 TRIM24 (0.53)
Diethylamine SCHEMBL9301198 0.86 NFE2L2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5838 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103371-B EGFR inhibitor and preparation method and application thereof SHANDONG NEW TIME PHARMACEUTICAL Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-121574130-A Synthesis method of pyrazolo [1,2-b ] phthalazine-5, 10-dione derivative as drug intermediate and catalytic system for synthesis 南京苏亦欣医药科技有限公司 2026-02-27 CN claimed
US-20250329799-A1 SYSTEM AND METHOD FOR IMPROVED BATTERY SAFETY Anthro Energy, Inc. (US) 2025-10-23 US claimed
CN-116606265-B Protocatechu derivative and synthesis method and application thereof 山西大学 2025-05-02 CN claimed
US-20250136445-A1 HYDROGEN PEROXIDE MANUFACTURING PROCESS AND MANUFACTURING SYSTEM BASED ON PHOTOCHEMICAL REACTION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-05-01 US claimed
CN-119899122-A Cyclobutylmethyl and phenyl substituted curcumin derivative and preparation method and application thereof 常州大学 2025-04-29 CN claimed
CN-119874581-A Organic sulfur micromolecule compound for lithium sulfur battery positive electrode material as well as preparation method and application thereof 上海屹锂新能源科技有限公司 2025-04-25 CN claimed
CN-119841715-A Method for directly preparing aromatic ether compound from aromatic aldehyde, ketone and phenol 湖南第一师范学院 2025-04-18 CN claimed
US-20250122202-A1 EGFR INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF SHANDONG NEW TIME PHARMACEUTICAL CO., LTD. (CN) 2025-04-17 US claimed
CN-119823576-A Modified polydimethylsiloxane self-repairing elastomer material and preparation method thereof 海南师范大学 2025-04-15 CN claimed
EP-0563916-B1 (1H-Indol-1-yl)-2-(amino)acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, intermediates and a process for their preparation and their use as medicaments HOECHST ROUSSEL PHARMA (US) 1995-08-16 EP claimed
EP-0439321-B1 Thiazolidine derivatives having anti-hypertensive activity and their therapeutic use SANKYO CO (JP) 1995-03-15 EP claimed
US-5319096-A Neuroprotective agent HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1994-06-07 US claimed
EP-0563916-A1 (1H-Indol-1-yl)-2-(amino)acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, intermediates and a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1993-10-06 EP claimed
US-5106999-A PROCESS FOR PREPARING DIBENZYLIDENE-D-SORBITOL COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1992-04-21 US claimed
WO-1992000301-A1 PROCESS FOR PREPARING DIBENZYLIDENE-D-SORBITOL COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1992-01-09 WO claimed
US-5049551-A Antitumor UBE INDUSTRIES, LTD. (JP) 1991-09-17 US claimed
EP-0439321-A2 Thiazolidine derivatives having anti-hypertensive activity and their therapeutic use Sankyo Company Limited (JP) 1991-07-31 EP claimed
EP-0400610-A1 5-Fluorouracil derivatives UBE INDUSTRIES, LTD. (JP) 1990-12-05 EP claimed
US-4072703-A HUMAN AND VETERINARY MEDICINE CHIMIE & BIOLOGIE (FR) 1978-02-07 US claimed