Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.75 |
| ▸ | GLA | P06280 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.75 |
| ▸ | BLM | P54132 | 1/20 | 0.75 |
| ▸ | CA1 | P00915 | 10/20 | 0.50 |
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA9 | Q16790 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6338087 | 1.00 | RECQL (0.75) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL1416476 | 0.96 | RECQL (0.75) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL1416646 | 0.96 | RECQL (0.75) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL1416798 | 0.93 | RECQL (0.69) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL4427096 | 0.92 | TSHR (0.62) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL2761119 | 0.90 | RECQL (0.66) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL25262176 | 0.86 | RECQL (1.00) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL21550444 | 0.86 | RECQL (0.91) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL22283884 | 0.86 | RECQL (0.91) | RECQLGLAHPGDTSHRMAPK1 | |
| Lithium Ion SCHEMBL25256858 | 0.86 | RECQL (0.91) | RECQLGLAHPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8025010-B1 | Method for reducing charge retention properties of solid propellants | ALLIANT TECHSYSTEMS INC. (US) | 2011-09-27 | — | — | US | disclosed |