Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168268 | 0.94 | APP (0.59) | APPNR2F2MCHR1MEN1KMT2A | |
| SCHEMBL26668462 | 0.84 | HRH3 (0.44) | APPNR2F2MCHR1MEN1KMT2A | |
| SCHEMBL9672111 | 0.84 | MMP2 (0.50) | NR2F2L3MBTL1HRH3SMN1; SMN2MMP2 | |
| SCHEMBL28842576 | 0.83 | MCHR1 (0.55) | APPMCHR1ESR2NPC1TP53 | |
| SCHEMBL6248269 | 0.79 | APP (0.55) | APPMEN1KMT2AHRH3KCNH2 | |
| SCHEMBL26668449 | 0.79 | MMP2 (0.48) | HRH3MMP2MMP3MMP13 | |
| SCHEMBL17616892 | 0.78 | MMP2 (0.46) | NR2F2L3MBTL1HRH3SMN1; SMN2MMP2 | |
| SCHEMBL20607767 | 0.78 | HRH3 (0.48) | APPHRH3MMP2 | |
| SCHEMBL15014175 | 0.77 | APP (0.88) | APPMCHR1MEN1KMT2AESR2 | |
| SCHEMBL6446069 | 0.77 | MMP2 (0.55) | APPL3MBTL1HRH3SMN1; SMN2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011211-A1 | DEOXYNOJIRIMYCIN DERIVATIVES AS GLUCOSIDASE INHIBITORS | EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. (US) | 2022-01-13 | — | — | WO | disclosed |