Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 7/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26668462 | 0.95 | HRH3 (0.44) | HRH3APPMMP2MMP12GABRP | |
| SCHEMBL13170580 | 0.84 | APP (0.48) | APPMMP2FFAR1 | |
| SCHEMBL28687083 | 0.84 | HRH3 (0.54) | HRH3APPMMP2MMP12ALDH1A1 | |
| SCHEMBL20681007 | 0.83 | HAO1 (0.40) | HRH3APPMMP2GABRPGABRD | |
| SCHEMBL6168268 | 0.82 | APP (0.59) | HRH3APPMMP2MMP12ALDH1A1 | |
| SCHEMBL21715143 | 0.80 | APP (0.41) | APPMMP2FFAR1FYN | |
| SCHEMBL24197392 | 0.78 | APP (0.53) | HRH3APPMMP2 | |
| SCHEMBL15010951 | 0.78 | HRH3 (0.59) | HRH3 | |
| SCHEMBL9511351 | 0.77 | ACHE (0.43) | APPFFAR1LMNA | |
| SCHEMBL3589633 | 0.77 | NQO1 (0.50) | APPMMP2FYNKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971191-A1 | BORON-CONTAINING SMALL MOLECULES | Bill And Melinda Gates Foundation (US) | 2022-03-23 | — | — | EP | disclosed |
| CN-113563368-A | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-10-29 | — | — | CN | disclosed |
| CN-113321672-A | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-08-31 | — | — | CN | disclosed |
| EP-3423065-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2021-07-21 | — | — | EP | disclosed |
| CN-109195608-B | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-05-11 | — | — | CN | disclosed |
| US-10919916-B2 | Boron-containing small molecules | BILL & MELINDA GATES FOUNDATION (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200247827-A1 | BORON-CONTAINING SMALL MOLECULES | BILL & MELINDA GATES FOUNDATION (US) | 2020-08-06 | — | — | US | disclosed |
| US-10611780-B2 | Boron-containing small molecules | BILL AND MELINDA GATES FOUNDATION (US) | 2020-04-07 | — | — | US | disclosed |
| US-20190077814-A1 | BORON-CONTAINING SMALL MOLECULES | GATES FOUNDATION | 2019-03-14 | — | — | US | disclosed |
| EP-3423065-A1 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077814-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BLVRB, BTD | HRH3 512/4885APP 4390/4885MMP2 2259/4885 |
| US-10919916-B2 | Boron-containing small molecules | BCL6B, BLVRB, BTD | HRH3 512/4885APP 4390/4885MMP2 2259/4885 |
| US-10611780-B2 | Boron-containing small molecules | BCL6B, BLVRB, BTD | HRH3 512/4885APP 4390/4885MMP2 2259/4885 |
| US-20200247827-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BLVRB, BTD | HRH3 512/4885APP 4390/4885MMP2 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.