Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325180 | 0.77 | RAB9A (0.34) | — | |
| SCHEMBL209495 | 0.76 | — | — | |
| SCHEMBL40173 | 0.74 | — | — | |
| SCHEMBL8200418 | 0.74 | CXCR4 (0.53) | CXCR4SOS1SOS2PHGDH | |
| SCHEMBL2772577 | 0.74 | CXCR4 (0.44) | CXCR4SOS1SOS2PHGDH | |
| Methylpiperazine SCHEMBL7566544 | 0.74 | ALDH1A1 (0.53) | CXCR4SOS1SOS2PHGDH | |
| SCHEMBL272114 | 0.74 | — | — | |
| SCHEMBL2621589 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL28503994 | 0.74 | RAB9A (0.38) | — | |
| Methylpiperazine SCHEMBL28185035 | 0.74 | ALDH1A1 (0.41) | CXCR4SOS1SOS2PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11224601-B1 | Compounds that inhibits MCL-1 protein | AMGEN INC. (US) | 2022-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11224601-B1 | Compounds that inhibits MCL-1 protein | MCL1, BCL9, BCL2L1 | CXCR4 2323/4885SOS1 390/4885SOS2 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.