Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 9/20 | 0.49 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21439579 | 0.94 | CFD (0.58) | CFDSUCNR1F11TPSB2MAPT | |
| SCHEMBL24200062 | 0.84 | CFD (0.44) | CFDMAPTPKMKMT2AMEN1 | |
| SCHEMBL21439756 | 0.83 | CFD (0.43) | CFDMAPTPKMP2RX7KMT2A | |
| SCHEMBL21439643 | 0.81 | CFD (0.73) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL21439718 | 0.79 | CFD (0.79) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL21455336 | 0.77 | CFD (0.79) | CFDSUCNR1F11TPSB2P2RX7 | |
| SCHEMBL21439681 | 0.77 | CFD (0.59) | CFDSUCNR1F11TPSB2 | |
| SCHEMBL21439761 | 0.76 | CFD (0.49) | CFDMAPTALDH1A1PKMKMT2A | |
| SCHEMBL30358694 | 0.76 | CFD (0.49) | CFDMAPTALDH1A1PKMKMT2A | |
| SCHEMBL21437767 | 0.75 | CFD (0.59) | CFDSUCNR1F11TPSB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |