Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21439756 | 0.91 | CFD (0.43) | CFDPKMKMT2ALMNAMEN1 | |
| SCHEMBL24200068 | 0.84 | CFD (0.49) | CFDPKMKMT2AMEN1KDM4E | |
| SCHEMBL30358694 | 0.83 | CFD (0.49) | CFDPKMKMT2ALMNAMEN1 | |
| SCHEMBL21439761 | 0.83 | CFD (0.49) | CFDPKMKMT2ALMNAMEN1 | |
| SCHEMBL21439579 | 0.83 | CFD (0.58) | CFDPKMMAPT | |
| SCHEMBL21439726 | 0.80 | PKM (0.43) | CFDPKMKMT2ALMNAMEN1 | |
| SCHEMBL23616897 | 0.80 | PKM (0.43) | CFDPKMKMT2ALMNAMEN1 | |
| SCHEMBL21439718 | 0.76 | CFD (0.79) | CFD | |
| SCHEMBL28516387 | 0.76 | CFD (0.56) | CFD | |
| SCHEMBL21439731 | 0.76 | CFD (0.47) | CFDPKMKMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |