Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.49 |
| ▸ | VEGFA | P15692 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4489433 | 0.95 | MEN1 (0.51) | SPHK2SPHK1MEN1KMT2AOPRD1 | |
| Hydrochloric Acid SCHEMBL6092398 | 0.94 | MEN1 (0.50) | MEN1KMT2AOPRD1 | |
| SCHEMBL8414527 | 0.91 | SPHK2 (0.47) | SPHK2SPHK1VEGFAEGLN1FAAH | |
| SCHEMBL9550064 | 0.87 | SPHK2 (0.51) | SPHK2SPHK1FAAHOPRD1 | |
| SCHEMBL2446144 | 0.87 | SPHK2 (0.51) | SPHK2SPHK1FAAHOPRD1 | |
| SCHEMBL4725155 | 0.87 | SPHK2 (0.51) | SPHK2SPHK1FAAHOPRD1 | |
| SCHEMBL11199979 | 0.85 | SPHK2 (0.50) | SPHK2SPHK1VEGFAEGLN1FAAH | |
| Hydrochloric Acid SCHEMBL8547793 | 0.85 | SPHK2 (0.50) | SPHK2SPHK1FAAHOPRD1 | |
| Hydrochloric Acid SCHEMBL8541840 | 0.85 | SPHK2 (0.50) | SPHK2SPHK1FAAHOPRD1 | |
| SCHEMBL7272434 | 0.85 | OPRD1 (0.47) | MEN1KMT2AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127206-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-28 | — | — | US | disclosed |
| EP-3939954-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127206-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | MGMT, FANCD2, ADAR | SPHK2 507/4885SPHK1 868/4885VEGFA 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.