SCHEMBL242001

SCHEMBL242001

N#CCCc1cc[c]cc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MMP9 P14780 1/20 0.35
MMP13 P45452 1/20 0.35
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
EGFR P00533 1/20 0.32
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764230 0.86 MEN1 (0.64) MEN1KMT2AALDH1A1TDP1MMP9
SCHEMBL267286 0.85 MEN1 (0.41) MEN1KMT2AALDH1A1TDP1
SCHEMBL27484461 0.83 MEN1 (0.40) MEN1KMT2A
SCHEMBL6576818 0.80 GFER (0.40) MEN1KMT2AALDH1A1TDP1
Benzene SCHEMBL28469748 0.79 MEN1 (0.70) MEN1KMT2AALDH1A1TDP1NR1H2
SCHEMBL8763175 0.79 MEN1 (0.56) MEN1KMT2AALDH1A1TDP1MMP9
SCHEMBL9552869 0.79 KMT2A (0.56) MEN1KMT2AALDH1A1TDP1MMP9
SCHEMBL13618845 0.79 MEN1 (0.70) MEN1KMT2AALDH1A1TDP1NR1H2
SCHEMBL181108 0.79 MEN1 (0.70) MEN1KMT2AALDH1A1TDP1NR1H2
SCHEMBL5702908 0.77 MEN1 (0.33) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778125-B Aryl phenol compound and synthesis method and application thereof 华东师范大学 2023-02-17 CN claimed
CN-112778125-A Aryl phenol compound and synthesis method and application thereof 华东师范大学 2021-05-11 CN claimed
WO-2013055910-A1 MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2013-04-18 WO claimed
US-8231941-B2 Procedure for preparing redox-active polymers on surfaces THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-31 US claimed
US-20100330284-A1 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-12-30 US claimed
CN-100577410-C Method for preparing redox-active polymers on surfaces UNIV CALIFORNIA 2010-01-06 CN claimed
EP-1620885-B1 ORGANIC POLYMERS, ELECTRONIC DEVICES, AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2009-08-12 EP claimed
EP-1635821-B1 4-BROMO-5-(2-CHLORO-BENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID (PHENYL)AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES ELAN PHARM INC (US) 2009-07-08 EP claimed
US-7473652-B2 Organic polymers, electronic devices, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-01-06 US claimed
US-7452572-B1 Procedure for preparing redox-active polymers on surfaces THE NORTH CAROLINA STATE UNIVERSITY (US) 2008-11-18 US claimed
WO-2005017953-A2 IN SITU PATTERNING OF ELECTROLYTE FOR MOLECULAR INFORMATION STORAGE DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-02-24 WO claimed
US-20050032868-A1 Selected substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists ELAN PHARMACEUTICALS, INC. 2005-02-10 US claimed
US-20050019592-A1 Organic polymers, laminates, and capacitors 3M INNOVATIVE PROPERTIES COMPANY 2005-01-27 US claimed
WO-2004102690-A2 ORGANIC POLYMERS, LAMINATES, AND CAPACITORS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-11-25 WO claimed
WO-2004102652-A1 ORGANIC POLYMERS, ELECTRONIC DEVICES, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-11-25 WO claimed
WO-2004099155-A2 4-BROMO-5-(2-CHLORO-BENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID (PHENYL) AMIDE DERIVATES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMATORY DISEASES ELAN PHARMACEUTICALS, INC. (US) 2004-11-18 WO claimed
US-20040222412-A1 Organic polymers, electronic devices, and methods 3M INNOVATIVE PROPERTIES COMPANY 2004-11-11 US claimed
US-20040120180-A1 Variable-persistence molecular memory devices and methods of operation thereof NORTH CAROLINA STATE UNIVERSITY 2004-06-24 US claimed
WO-2003102153-A2 CELL MIGRATION INHIBITING COMPOSITIONS AND METHODS AND COMPOSITIONS FOR TREATING CANCER AVOLIX PHARMACEUTICALS (US) 2003-12-11 WO claimed
US-4275184-A HYDROSILATION OF POLYDIMETHYL SILOXANE RHONE-POULENC INDUSTRIES (FR) 1981-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050032868-A1 Selected substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists BDKRB1, BDKRB2, BRS3 MEN1 1180/4885KMT2A 4030/4885ALDH1A1 3108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.