SCHEMBL267286

SCHEMBL267286

N#CCCCc1cc[c]cc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 3/20 0.35
MPO P05164 1/20 0.34
SLC6A4 P31645 1/20 0.34
HIF1A Q16665 2/20 0.33
EPAS1 Q99814 2/20 0.33
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TBXAS1 P24557 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27484461 0.93 MEN1 (0.40) MEN1KMT2AATML3MBTL1TSHR
SCHEMBL9671911 0.87 MEN1 (0.46) MEN1KMT2AATML3MBTL1TSHR
SCHEMBL242001 0.85 MEN1 (0.56) MEN1KMT2AALDH1A1TDP1
SCHEMBL11803736 0.82 MAOA (0.40) L3MBTL1SLC6A4HIF1AHSD17B10ALDH1A1
SCHEMBL9552742 0.81 TSHR (0.48) MEN1KMT2AATML3MBTL1TSHR
SCHEMBL181369 0.81 MEN1 (0.52) MEN1KMT2AATML3MBTL1
SCHEMBL9553570 0.81 TSHR (0.48) MEN1KMT2AATML3MBTL1TSHR
SCHEMBL11690401 0.79 SIGMAR1 (0.41) TSHRSLC6A4HIF1AHSD17B10ALDH1A1
SCHEMBL27354175 0.79 CYP3A4 (0.36) HSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL9324490 0.79 MEN1 (0.50) MEN1KMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118225906-A Method for detecting 2-chloropropane in levobupivacaine hydrochloride 珠海润都制药股份有限公司 2024-06-21 CN claimed
CN-118225956-A Determination analysis method for methyl aminocrotonate content in lacidipine 上海奥博生物医药股份有限公司 2024-06-21 CN claimed
CN-117805257-A Method for detecting residual benzene in carbomer 湖州市瑞民医疗科技有限公司 2024-04-02 CN claimed
CN-116381075-B GC-MS (gas chromatography-mass spectrometry) -based method for detecting C0 in D5 江苏和汇医药科技有限公司 2024-03-12 CN claimed
EP-3819634-B1 DETECTION METHOD FOR N-NITROSODIMETHYLAMINE IMPURITIES ZHEJIANG HUAHAI PHARM CO LTD (CN) 2024-02-21 EP claimed
CN-117517543-A Synchronous detection method for content of various organophosphorus flame retardants in soil 江苏康达检测技术股份有限公司 2024-02-06 CN claimed
CN-116500172-B Detection method of amine solvent in acidic substrate 成都普康唯新生物科技有限公司 2023-09-05 CN claimed
CN-114624372-B Method for detecting acetic acid in air and gas chromatograph 大连大特气体有限公司 2023-08-15 CN claimed
CN-116577422-A Method for detecting propellant 1, 2-tetrafluoroethane and cosolvent ethanol in inhalation aerosol 武汉药品医疗器械检验所 2023-08-11 CN claimed
CN-116500172-A Detection method of amine solvent in acidic substrate 成都普康唯新生物科技有限公司 2023-07-28 CN claimed
CN-110658287-A Method for analyzing potential genotoxic impurities in sevelamer carbonate bulk drug 江苏海悦康医药科技有限公司 2020-01-07 CN claimed
CN-110412190-A The analysis system and its analysis method of methane and non-methane total hydrocarbons BEIJING SDL TECHNOLOGY CO LTD 2019-11-05 CN claimed
EP-3285648-A2 COVERING CAP Vasema GmbH (AT) 2018-02-28 EP claimed
WO-2016156585-A2 COVERING CAP VASEMA DIAGNOSTICS AG (CH) 2016-10-06 WO claimed
US-20120270330-A1 Hybrid Separation and Detection Device for Chemical Detection and Analysis ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2012-10-25 US claimed
WO-2011031500-A2 A HYBRID SEPARATION AND DETECTION DEVICE FOR CHEMICAL DETECTION AND ANALYSIS ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2011-03-17 WO claimed
US-7390349-B2 Polyhydrosiloxane compounds and articles and use thereof AGILENT TECHNOLOGIES, INC. (US) 2008-06-24 US claimed
EP-1750945-A2 A PROCESS AND SYSTEM FOR PRINTING IMAGES ON ABSORPTIVE SURFACES Kornit Digital Ltd. (IL) 2007-02-14 EP claimed
US-20060027098-A1 Polyhydrosiloxane compounds and articles and use thereof AGILENT TECHNOLOGIES INC 2006-02-09 US claimed
WO-2005115089-A2 A PROCESS AND SYSTEM FOR PRINTING IMAGES ON ABSORPTIVE SURFACES KORNIT DIGITAL LTD. (IL) 2005-12-08 WO claimed