SCHEMBL2420022

SCHEMBL2420022

CCCCOC(=O)Cc1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HTT P42858 1/20 0.49
ALDH1A1 P00352 4/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CTBP2 P56545 1/20 0.46
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 1/20 0.46
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.45
CNR2 P34972 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ESR1 P03372 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2417592 0.90 CTBP2 (0.49) HTTALDH1A1KMT2ACTBP2HSD17B10
SCHEMBL2422452 0.89 TDP1 (0.47) TSHRTDP1L3MBTL1HTTALDH1A1
SCHEMBL28362405 0.85 TSHR (0.54) TSHRTDP1L3MBTL1ALDH1A1MEN1
SCHEMBL28366032 0.84 TSHR (0.53) TSHRTDP1L3MBTL1ALDH1A1MEN1
SCHEMBL513530 0.83 PKM (0.53) ALDH1A1KMT2ACTBP2KDM4ECYP3A4
SCHEMBL13109329 0.83 TTR (0.68) TSHRKMT2ACYP3A4MAPK1LMNA
SCHEMBL8431889 0.83 TSHR (0.51) TSHRTDP1L3MBTL1ALDH1A1MEN1
SCHEMBL28366194 0.83 TSHR (0.51) TSHRTDP1L3MBTL1ALDH1A1MEN1
SCHEMBL28512693 0.83 TSHR (0.51) TSHRTDP1L3MBTL1ALDH1A1MEN1
SCHEMBL1555236 0.82 ALDH1A1 (0.60) TSHRTDP1L3MBTL1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278404-B2 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20110224390-A1 PROCESS FOR PRODUCING COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-15 US disclosed
US-7262258-B2 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-28 US disclosed
US-20070088139-A1 PROCESS FOR PRODUCING COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED 2007-04-19 US disclosed
US-20050014914-A1 Process for producing copolymer SUMITOMO CHEMICAL COMPANY, LIMITED 2005-01-20 US disclosed
CN-1042639-C Process for the preparation of low molecular weight copolymers of ethylene and at least one other 1-olefin DSM NV (NL) 1999-03-24 CN disclosed
US-5728911-A CATALYTIC SOLUTION COPOLYMERIZATION OF ETHYLENE WITH POLYUNSATURATED MONOMER DSM COPOLYMER, INC. (US) 1998-03-17 US disclosed
EP-0705284-B1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1997-07-09 EP disclosed
CN-1125954-A Process for the preparation of low molecular weight copolymers of ethylene and at least one other 1-olefin DSM NV (NL) 1996-07-03 CN disclosed
EP-0705284-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1996-04-10 EP disclosed
WO-1995000564-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM N.V. (NL) 1995-01-05 WO disclosed
EP-0044119-B1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE STAMICARBON B.V. (NL) 1985-05-29 EP disclosed
US-4435552-A COORDINATION CATALYST CONTAINING HALOACYL COMPOUND STAMICARBON B.V. (NL) 1984-03-06 US disclosed
EP-0044119-A2 Process for the preparation of copolymers of ethylene with at least one other 1-alkene STAMICARBON B.V. (NL) 1982-01-20 EP disclosed