Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25919838 | 0.90 | MEN1 (0.34) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL21455829 | 0.90 | MEN1 (0.34) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL21455958 | 0.90 | MAPT (0.32) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL24199970 | 0.89 | PTGS2 (0.34) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL24200253 | 0.88 | ALDH1A1 (0.39) | MEN1KMT2APOLBHPGDALDH1A1 | |
| SCHEMBL25918089 | 0.88 | ALDH1A1 (0.39) | MEN1KMT2APOLBHPGDALDH1A1 | |
| SCHEMBL21561946 | 0.81 | MEN1 (0.33) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL21455199 | 0.81 | MAOB (0.35) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL25918206 | 0.81 | MAOB (0.35) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL24200127 | 0.81 | MEN1 (0.35) | MEN1KMT2AALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |