Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201089 | 0.87 | EPHX2 (0.34) | — | |
| SCHEMBL24201269 | 0.86 | EPHX2 (0.33) | — | |
| SCHEMBL24201130 | 0.86 | EPHX2 (0.33) | — | |
| SCHEMBL24201320 | 0.79 | EPHX2 (0.33) | — | |
| SCHEMBL24201145 | 0.78 | ALDH1A1 (0.33) | HSD11B1ALDH1A1POLBKDM4EHTT | |
| SCHEMBL24201095 | 0.78 | EPHX2 (0.32) | — | |
| SCHEMBL24201326 | 0.78 | EPHX2 (0.32) | — | |
| SCHEMBL24201102 | 0.78 | EPHX2 (0.32) | — | |
| SCHEMBL24201267 | 0.77 | ALOX5AP (0.31) | — | |
| SCHEMBL24201139 | 0.74 | CYP19A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3618833-B1 | TRIPARTITE ANDROGEN RECEPTOR ELIMINATORS, METHODS AND USES THEREOF | SPG THERAPEUTICS INC (US) | 2022-01-19 | — | — | EP | disclosed |