Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201139 | 0.84 | CYP19A1 (0.33) | ALDH1A1 | |
| SCHEMBL24201320 | 0.82 | EPHX2 (0.33) | EPHX2 | |
| SCHEMBL24201095 | 0.81 | EPHX2 (0.32) | EPHX2 | |
| SCHEMBL24201102 | 0.81 | EPHX2 (0.32) | EPHX2 | |
| SCHEMBL24201326 | 0.81 | EPHX2 (0.32) | EPHX2 | |
| SCHEMBL24201098 | 0.79 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL24201081 | 0.79 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL24201142 | 0.78 | HSD11B1 (0.33) | ALDH1A1KDM4EHTTHSD11B1POLB | |
| SCHEMBL24201152 | 0.75 | OPRK1 (0.30) | — | |
| SCHEMBL24201283 | 0.75 | OPRK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3618833-B1 | TRIPARTITE ANDROGEN RECEPTOR ELIMINATORS, METHODS AND USES THEREOF | SPG THERAPEUTICS INC (US) | 2022-01-19 | — | — | EP | disclosed |