Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 13/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19593827 | 0.75 | SLC9A3 (0.41) | SLC9A3 | |
| SCHEMBL23469883 | 0.72 | SLC9A3 (0.36) | SLC9A3 | |
| SCHEMBL20404475 | 0.72 | SLC9A3 (0.36) | SLC9A3 | |
| SCHEMBL19593907 | 0.69 | SLC9A3 (0.36) | SLC9A3 | |
| SCHEMBL24201173 | 0.68 | LTA4H (0.33) | SLC9A3 | |
| SCHEMBL19593895 | 0.68 | SLC9A3 (0.36) | SLC9A3 | |
| SCHEMBL23469959 | 0.67 | SLC9A3 (0.51) | SLC9A3 | |
| SCHEMBL13467244 | 0.67 | SLC9A3 (0.64) | SLC9A3 | |
| SCHEMBL19593418 | 0.67 | SLC9A3 (0.53) | SLC9A3 | |
| SCHEMBL24201229 | 0.66 | SLC9A3 (0.48) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939964-A1 | COMBINATIONS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS | Ardelyx, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |