Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17457697 | 0.97 | ALDH1A1 (0.60) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL19509240 | 0.88 | EPHX2 (0.62) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL24201340 | 0.86 | EPHX2 (0.62) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL24201247 | 0.86 | EPHX2 (0.62) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL19509238 | 0.84 | EPHX2 (0.81) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL17471623 | 0.84 | EPHX2 (0.61) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL15597241 | 0.84 | EPHX2 (0.61) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL22225447 | 0.84 | EPHX2 (0.61) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL19500375 | 0.84 | EPHX2 (0.58) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL17457691 | 0.84 | ALDH1A1 (0.61) | EPHX2ALDH1A1CYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3618833-B1 | TRIPARTITE ANDROGEN RECEPTOR ELIMINATORS, METHODS AND USES THEREOF | SPG THERAPEUTICS INC (US) | 2022-01-19 | — | — | EP | disclosed |