Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CFB | P00751 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054518 | 0.83 | ACHE (0.38) | PARP1 | |
| SCHEMBL25648517 | 0.83 | CFB (0.39) | PARP1CFB | |
| SCHEMBL25648972 | 0.79 | PARP1 (0.44) | PARP1CFB | |
| SCHEMBL23783633 | 0.73 | GAA (0.54) | GAAALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL6314736 | 0.73 | HTR2A (0.36) | PARP1GAAALDH1A1KDM4ETDP1 | |
| SCHEMBL23863696 | 0.71 | CFB (0.48) | GAAALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL23641611 | 0.70 | HTR2A (0.37) | PARP1GAAALDH1A1KDM4EPOLB | |
| SCHEMBL1427544 | 0.70 | GAA (0.55) | GAAALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL19446025 | 0.69 | CFB (0.74) | CFB | |
| SCHEMBL24201510 | 0.68 | MEN1 (0.46) | GAAALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939591-A1 | QUINAZOLINE AND INDOLE COMPOUNDS TO TREAT MEDICAL DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |