Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23783633 | 0.75 | GAA (0.54) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL27423516 | 0.72 | ACHE (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1427544 | 0.71 | GAA (0.55) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL27421652 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL24835300 | 0.71 | MTNR1A (0.40) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL16883429 | 0.71 | GAA (0.67) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL23863696 | 0.70 | CFB (0.48) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL1427541 | 0.70 | GAA (0.61) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL25854573 | 0.70 | KDM4E (0.60) | MEN1KMT2AALDH1A1TSHRGAA | |
| SCHEMBL24835185 | 0.69 | MAPK1 (0.32) | MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939591-A1 | QUINAZOLINE AND INDOLE COMPOUNDS TO TREAT MEDICAL DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |