Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27834366 | 0.88 | HTT (0.42) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL24202214 | 0.88 | HTT (0.45) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL20095269 | 0.82 | HTT (0.47) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL21790823 | 0.81 | HTT (0.43) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL28898701 | 0.80 | ALOX5 (0.48) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL3672142 | 0.80 | KDM4E (0.44) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL20095219 | 0.79 | ALOX5 (0.43) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL27852474 | 0.77 | AKT1 (0.46) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL12012725 | 0.77 | KDM4E (0.41) | HTTKDM4EHSD17B10TP53GAA | |
| SCHEMBL27698991 | 0.77 | KDM4E (0.41) | HTTKDM4EHSD17B10TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315126-B1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | JENKEM TECH CO LTD TIANJIN (CN) | 2022-01-19 | — | — | EP | disclosed |