Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3083354 | 0.90 | LMNA (0.47) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL11579831 | 0.89 | KDM4E (0.44) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL28898701 | 0.85 | ALOX5 (0.48) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL3156904 | 0.84 | KDM4E (0.52) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL1224632 | 0.84 | ACHE (0.41) | KDM4EHTTHSD17B10GAALMNA | |
| SCHEMBL27834366 | 0.84 | HTT (0.42) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL21771928 | 0.83 | KDM4E (0.40) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL27865228 | 0.82 | LMNA (0.40) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL27671451 | 0.82 | LMNA (0.40) | KDM4EHTTHSD17B10TP53GAA | |
| SCHEMBL12012725 | 0.82 | KDM4E (0.41) | KDM4EHTTHSD17B10TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2218330-A1 | Process for the preparation of 2-ethyl-4,6-dimethylphenyl acetic acid by reacting 2-ethyl-4,6-dimethylbromobenzene with tert.-butylacetate | Bayer CropScience AG (DE) | 2010-08-18 | — | — | EP | disclosed |