SCHEMBL2420259

SCHEMBL2420259

C=CC[Si]1(OC(=O)C(=C)C)CCCCO1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10344543 0.82 TSHR (0.36) ALDH1A1
SCHEMBL15986792 0.81 ALDH1A1 (0.31) ALDH1A1
SCHEMBL28314103 0.72 ALDH1A1 (0.33) ALDH1A1
SCHEMBL9546018 0.72 ALDH1A1 (0.33) ALDH1A1
Methacrylic Acid SCHEMBL9546433 0.69 ALDH1A1 (0.31) ALDH1A1
SCHEMBL27550344 0.66 ALDH1A1 (0.52) ALDH1A1
SCHEMBL10696392 0.66
SCHEMBL5024468 0.65 TSHR (0.42) ALDH1A1
SCHEMBL27389968 0.64 TSHR (0.49) ALDH1A1
SCHEMBL28800332 0.62 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379462-B1 Vinylic macromers containing perfluoropolyalkylether and polyalkylether segments, polymers, copolymers and ophthalmic devices made therefrom CIBA GEIGY AG (CH) 1995-02-22 EP claimed
EP-0456611-B1 Hydroxyethyl cellulose derivatives containing pendant (meth)acryloyl units bound through urethane groups and hydrogel contact lenses made therefrom CIBA GEIGY AG (CH) 1994-03-16 EP claimed
US-5157093-A High oxygen permeability, wettability, and mechanical strength CIBA-GEIGY CORPORATION (US) 1992-10-20 US claimed
EP-0456611-A2 Hydroxyethyl cellulose derivatives containing pendant (meth)acryloyl units bound through urethane groups and hydrogel contact lenses made therefrom CIBA-GEIGY AG (CH) 1991-11-13 EP claimed
EP-0379462-A2 Vinylic macromers containing perfluoropolyalkylether and polyalkylether segments, polymers, copolymers and ophthalmic devices made therefrom CIBA-GEIGY AG (CH) 1990-07-25 EP claimed
US-4929692-A Crosslinked copolymers and ophthalmic devices made from vinylic macromers containing perfluoropolyalkyl ether and polyalkyl ether segments and minor amounts of vinylic comonomers CIBA-GEIGY CORPORATION (US) 1990-05-29 US claimed
US-8822573-B2 Chemical two-component mortar compound with improved adhesion to the surface of partially cleaned and/or moist holes in mineral substrates, and the use of such a chemical two-component mortar compound HILTI AKTIENGESELLSCHAFT (LI) 2014-09-02 US disclosed
US-20110236612-A1 Chemical two-component mortar compound with improved adhesion to the surface of partially cleaned and/or moist holes in mineral substrates, and the use of such a chemical two-component mortar compound HILTI AKTIENGESELLSCHAFT (LI) 2011-09-29 US disclosed
EP-0379462-B1 Vinylic macromers containing perfluoropolyalkylether and polyalkylether segments, polymers, copolymers and ophthalmic devices made therefrom CIBA GEIGY AG (CH) 1995-02-22 EP disclosed
EP-0456611-B1 Hydroxyethyl cellulose derivatives containing pendant (meth)acryloyl units bound through urethane groups and hydrogel contact lenses made therefrom CIBA GEIGY AG (CH) 1994-03-16 EP disclosed
US-5157093-A High oxygen permeability, wettability, and mechanical strength CIBA-GEIGY CORPORATION (US) 1992-10-20 US disclosed
EP-0456611-A2 Hydroxyethyl cellulose derivatives containing pendant (meth)acryloyl units bound through urethane groups and hydrogel contact lenses made therefrom CIBA-GEIGY AG (CH) 1991-11-13 EP disclosed
US-5002978-A Soft hydrogel contact lenses; intraocular lenses CIBA-GEIGY CORPORATION (US) 1991-03-26 US disclosed
EP-0379462-A2 Vinylic macromers containing perfluoropolyalkylether and polyalkylether segments, polymers, copolymers and ophthalmic devices made therefrom CIBA-GEIGY AG (CH) 1990-07-25 EP disclosed
US-4929692-A Crosslinked copolymers and ophthalmic devices made from vinylic macromers containing perfluoropolyalkyl ether and polyalkyl ether segments and minor amounts of vinylic comonomers CIBA-GEIGY CORPORATION (US) 1990-05-29 US disclosed