SCHEMBL5024468

SCHEMBL5024468

C=C(C)C(=O)OCC[Si]1(O)CCCCO1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
THRB P10828 1/20 0.40
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5014894 0.93 TSHR (0.46) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL9073350 0.78 TSHR (0.46) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL27389968 0.78 TSHR (0.49) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL5014818 0.77 TSHR (0.46) TSHRTHRBALDH1A1
Tetrahydrofuran SCHEMBL11126766 0.73 THRB (0.55) TSHRTHRBALDH1A1POLBAPEX1
Oxirane SCHEMBL3776781 0.70 THRB (0.61) TSHRTHRBALDH1A1POLBAPEX1
Cyclohexane SCHEMBL117214 0.70 THRB (0.65) TSHRTHRBALDH1A1POLBAPEX1
Cyclopropane SCHEMBL420362 0.70 THRB (0.65) TSHRTHRBALDH1A1POLBAPEX1
Cyclopentane SCHEMBL2397167 0.70 THRB (0.65) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL60085 0.70 THRB (0.65) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115277-B2 Porous polyolefin resin film MITSUBISHI PLASTICS, INC. (JP) 2015-08-25 US disclosed
US-20130236793-A1 POROUS POLYOLEFIN RESIN FILM MITSUBISHI PLASTICS, INC. (JP) 2013-09-12 US disclosed
EP-2626380-A1 POROUS POLYOLEFIN RESIN FILM Mitsubishi Plastics, Inc. (JP) 2013-08-14 EP disclosed
US-7393911-B2 Organosilicon fine particles and method of producing same TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2008-07-01 US disclosed
US-20060089478-A1 antireflection and antiblocking characteristics to synthetic polymer films and sheets when applied to their surface or caused to be contained, respectively, and adherence and slip characteristics to a skin care cosmetic material when caused to be contained TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2006-04-27 US disclosed