SCHEMBL24210342

SCHEMBL24210342

COc1cc(O)cc(C(=O)OCC(O)CO)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 6/20 0.46
ADRB1 P08588 6/20 0.46
ADRB3 P13945 6/20 0.46
CA12 O43570 3/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA7 P43166 3/20 0.45
CA9 Q16790 3/20 0.45
CA14 Q9ULX7 3/20 0.45
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42
PTPN1 P18031 1/20 0.41
SERPINE1 P05121 1/20 0.41
CNR2 P34972 2/20 0.41
ALDH1A1 P00352 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
BACE1 P56817 1/20 0.39
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13955651 0.81 SERPINE1 (0.60) CA12CA1CA2CA7CA9
SCHEMBL14092787 0.80 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL672587 0.79 PKM (0.58) ADRB2ADRB1ADRB3CA12CA1
SCHEMBL22509324 0.79 SERPINE1 (0.46) ADRB2ADRB1ADRB3SERPINE1ALDH1A1
SCHEMBL2179812 0.79 ADRB2 (0.69) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL2179816 0.79 ADRB2 (0.69) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL2179807 0.79 ADRB2 (0.69) ADRB2ADRB1ADRB3CA1CA2
SCHEMBL14374036 0.79 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL13183860 0.77 TSHR (0.54) TSHRMAPK1PTPN1CYP3A4
SCHEMBL24210603 0.76 AR (0.57) ADRB2ADRB1ADRB3CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220019141-A1 POSITIVE WORKING PHOTOSENSITIVE MATERIAL MERCK PATENT GMBH (DE) 2022-01-20 US disclosed