Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30401688 | 1.00 | CHEK1 (0.33) | CHEK1FLT3PLK3ITKHTR1B | |
| SCHEMBL17261999 | 0.85 | CHEK1 (0.36) | CHEK1FLT3PLK3ITKHTR1B | |
| SCHEMBL5484683 | 0.76 | KDM4E (0.53) | CHEK1FLT3PLK3ITKALDH1A1 | |
| SCHEMBL30039348 | 0.76 | KDM4E (0.53) | CHEK1FLT3PLK3ITKALDH1A1 | |
| SCHEMBL15505899 | 0.72 | MCHR1 (0.36) | CHEK1FLT3PLK3ITKALDH1A1 | |
| SCHEMBL24210984 | 0.70 | NOS1 (0.51) | CHEK1FLT3HTR1BALDH1A1HPGD | |
| SCHEMBL30402472 | 0.70 | NOS1 (0.51) | CHEK1FLT3HTR1BALDH1A1HPGD | |
| SCHEMBL31127684 | 0.70 | NOS1 (0.41) | CHEK1FLT3PLK3KDM4EHSD17B10 | |
| SCHEMBL16724769 | 0.70 | NOS1 (0.41) | CHEK1FLT3PLK3KDM4EHSD17B10 | |
| SCHEMBL25045526 | 0.69 | CHEK1 (0.42) | CHEK1FLT3PLK3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929693-B | Nitrogen-containing heterocyclic compound, pharmaceutical composition and application | 广州费米子科技有限责任公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2022012534-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | 广州费米子科技有限责任公司 | 2022-01-20 | — | — | WO | disclosed |
| CN-113929693-A | Nitrogen-containing heterocyclic compound, pharmaceutical composition and application | 广州费米子科技有限责任公司 | 2022-01-14 | — | — | CN | disclosed |