SCHEMBL24211024

SCHEMBL24211024

Cc1cc(-c2c3ccccc3c(-c3cc(C)cc(C(F)(F)F)c3)c3ccccc23)cc(C(F)(F)F)c1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.42
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
TAS2R14 Q9NYV8 1/20 0.39
IKBKB O14920 1/20 0.39
PTPN5 P54829 2/20 0.38
KIF11 P52732 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
NFE2L2 Q16236 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
ACHE P22303 1/20 0.37
TACR1 P25103 2/20 0.36
ENPP1 P22413 1/20 0.36
ESR1 P03372 1/20 0.36
DRD2 P14416 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
RAPGEF4 Q8WZA2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26748877 0.88 CYP1A2 (0.39) NOTUMIKBKBPTPN5TDP1ALDH1A1
SCHEMBL16882452 0.86 CNR1 (0.49) CNR1CNR2IKBKBKIF11TDP1
SCHEMBL14195756 0.86 KIF11 (0.47) KIF11ALDH1A1TSHRACHEENPP1
SCHEMBL31139502 0.84 CNR1 (0.47) CNR1CNR2IKBKBKIF11TDP1
SCHEMBL21344627 0.84 CNR1 (0.47) CNR1CNR2IKBKBKIF11TDP1
SCHEMBL12546554 0.83 ENPP1 (0.33) NOTUMCNR1CNR2TAS2R14IKBKB
SCHEMBL4266470 0.81 KIF11 (0.54) NOTUMTAS2R14PTPN5KIF11ALDH1A1
SCHEMBL22993192 0.81 TDP1 (0.49) CNR1CNR2KIF11TDP1ALDH1A1
SCHEMBL12567462 0.80 ENPP1 (0.33) NOTUMCNR1CNR2IKBKBTDP1
SCHEMBL26375466 0.80 NOTUM (0.41) NOTUMCNR1CNR2TAS2R14IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365286-B2 Polyarylether-based polymer with side chain in methoxypolyethylene glycols structure, solid polymer electrolyte and preparation methods therefor DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2022-06-21 US disclosed
US-20220017695-A1 POLYARYLETHER-BASED POLYMER WITH SIDE CHAIN IN POLYETHYLENE GLYCOL STRUCTURE, SOLID POLYMER ELECTROLYTE AND PREPARATION METHODS THEREFOR DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2022-01-20 US disclosed