SCHEMBL22993192

SCHEMBL22993192

FC(F)(F)c1cc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc(C(F)(F)F)c1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.49
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
KIF11 P52732 1/20 0.48
ESR1 P03372 2/20 0.48
TACR1 P25103 12/20 0.47
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
RXRG P48443 1/20 0.42
METAP2 P50579 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16882452 0.94 CNR1 (0.49) TDP1CNR1CNR2KIF11ESR1
SCHEMBL21344627 0.92 CNR1 (0.47) TDP1CNR1CNR2KIF11ESR1
SCHEMBL31139502 0.92 CNR1 (0.47) TDP1CNR1CNR2KIF11ESR1
SCHEMBL22978405 0.86 CNR2 (0.53) TDP1CNR2KIF11ESR1ALDH1A1
SCHEMBL24037857 0.85 CNR1 (0.43) TDP1CNR1CNR2KIF11ESR1
SCHEMBL22978403 0.83 KIF11 (0.71) KIF11ESR1ALDH1A1TSHR
SCHEMBL4399883 0.83 KIF11 (0.53) TDP1CNR2KIF11ESR1ALDH1A1
SCHEMBL24038260 0.82 ALOX5 (0.46) TDP1CNR1CNR2KIF11ESR1
SCHEMBL13932251 0.82 TDP1 (0.40) TDP1CNR1CNR2KIF11ESR1
SCHEMBL13932242 0.82 TDP1 (0.40) TDP1CNR1CNR2KIF11ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed