Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483213 | 0.85 | PDE3B (0.42) | GPR84PDE3BPDE3ALMNAPOLB | |
| SCHEMBL791861 | 0.81 | GPR84 (0.54) | GPR84PDE3BPDE3AKMT2A | |
| SCHEMBL28202924 | 0.79 | — | — | |
| SCHEMBL3639622 | 0.79 | GPR84 (0.51) | GPR84PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL26011808 | 0.74 | MEN1 (0.39) | GPR84PDE3BPDE3ALMNAPOLB | |
| SCHEMBL4016016 | 0.74 | PDE3B (0.51) | GPR84PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL26063160 | 0.73 | GPR84 (0.75) | GPR84PDE3ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL24211542 | 0.73 | GPR84 (0.75) | GPR84PDE3ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL10733971 | 0.72 | KMT2A (0.56) | GPR84KDM4EPDE3BPDE3ALMNA | |
| SCHEMBL4684337 | 0.71 | TBXAS1 (0.64) | TBXAS1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022012799-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-01-20 | — | — | WO | disclosed |